This is an uncurated list of recent (last month) publications in the field of ion channels and transporters in immunity, generated using an automated PubMed search. If you notice publications that are missing and should be included, please share your feedback with us, and we will do our best to review and add it to the list.
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Cheng HY, Chu J, Limjunyawong N, Chen J, Ye Y, Chen KH, Koylass N, Sun S, Dong X, Qiu Z
J Exp Med.
2025 Nov 3;
222
(11):
e20250312.
doi: 10.1084/jem.20250312.
Epub 2025 Aug 22.
Nov 3, 2025
In this study, Cheng et al. report that the proton-activated chloride (PAC) channel works as a phagosome “brake”, limiting acidification and protease activation in macrophages during bacterial infection. Deletion of PAC enhances macrophage bactericidal activities and prevents septicemia in mice by promoting STING signaling and gasdermin D secretion. –HYC/SF
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